| Identification | Back Directory | [Name]
MOCPAC | [CAS]
787549-26-2 | [Synonyms]
MOCPAC >=95% (HPLC), solid
Carbamic acid, N-[(1S)-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]-5-[(1-oxopropyl)amino]pentyl]-, phenylmethyl ester | [Molecular Formula]
C27H31N3O6 | [MDL Number]
MFCD08705325 | [MOL File]
787549-26-2.mol | [Molecular Weight]
493.55 |
| Chemical Properties | Back Directory | [Melting point ]
161 °C | [Boiling point ]
804.4±65.0 °C(Predicted) | [density ]
1.246±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: 21 mg/mL, soluble | [form ]
solid | [pka]
11.02±0.46(Predicted) | [color ]
White to off-white | [InChIKey]
BFDGUJKFQRJHJM-QFIPXVFZSA-N | [SMILES]
CCC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2 |
| Hazard Information | Back Directory | [Uses]
MOCPAC is an HDAC1 specific substrate[1]. | [Biological Activity]
Selective HDAC1 substrate (over HDAC6class I over class II). | [IC 50]
HDAC1 | [References]
[1] Sim?es-Pires CA, et al. Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS. J Vis Exp. 2017 Aug 10;(126):55878. DOI:10.3791/55878 |
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