| Identification | Back Directory | [Name]
DIMETHISTERONE | [CAS]
79-64-1 | [Synonyms]
Ovin
P 5048
Lutogan
Secrosteron
DIMETHISTERONE
6α,21-Dimethylethisterone
17β-Hydroxy-6α-methyl-17-(1-propynyl)androst-4-en-3-one | [EINECS(EC#)]
201-215-4 | [Molecular Formula]
C23H32O2 | [MDL Number]
MFCD00867870 | [MOL File]
79-64-1.mol | [Molecular Weight]
340.5 |
| Hazard Information | Back Directory | [Originator]
Oracon,Mead Johnson,US,1965 | [Definition]
ChEBI: Dimethisterone is a 3-hydroxy steroid. It has a role as an androgen. | [Manufacturing Process]
A solution of a Grignard reagent, employing 1-propyne (8 grams) was
prepared. To this reagent there was added the 3,3 ethylenedioxy derivative (4
grams) of 6-α-methylandrost-4-ene-3,17-dione in tetrahydrofuran (100 ml),
and the mixture heated under reflux for 3 hours. After decomposition of the
complex with aqueous ammonium chloride, the product was isolated with
ether and treated with 90% acetic acid (50 ml) for 30 minutes at 100°C. The
product obtained by pouring the mixture into water and extracting with ether
was crystallized from aqueous methanol. 17β-Hydroxy-6α-methyl-17α-(prop-
1-ynyl)androst-4-en-3-one formed plates MP 99° to 102°C. | [Therapeutic Function]
Progestin |
|
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