| Identification | Back Directory | [Name]
Pemafibrate (racemate) | [CAS]
848258-31-1 | [Synonyms]
K13675 (racemate)
Pemafibrate (racemate)
Butanoic acid, 2-[3-[[2-benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]-
2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid | [Molecular Formula]
C28H30N2O6 | [MDL Number]
MFCD30534401 | [MOL File]
848258-31-1.mol | [Molecular Weight]
490.55 |
| Hazard Information | Back Directory | [Description]
Pemafibrate racemate is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively.
h-PPARα|1 nM (EC50)|h-PPARδ|1.7 μM (EC50)
Pemafibrate racemate activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively[1]. | [Uses]
Pemafibrate racemate (K13675 racemate) is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively. | [IC 50]
h-PPARα: 1 nM (EC50); h-PPARδ: 1.7 μM (EC50) | [storage]
Store at -20°C | [References]
[1]. Yamazaki Y, et al. Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4689-93. Epub2007 May 24. |
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