| Identification | Back Directory | [Name]
Benzamide, N-[3-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-(dimethylamino)- | [CAS]
850665-21-3 | [Synonyms]
GSK248233A
Benzamide, N-[3-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-(dimethylamino)- | [Molecular Formula]
C25H24N8O3 | [MOL File]
850665-21-3.mol | [Molecular Weight]
484.51 |
| Hazard Information | Back Directory | [Uses]
GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1]. | [References]
[1] Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888. DOI:10.1371/journal.pone.0057888 |
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