| Identification | Back Directory | [Name]
1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) | [CAS]
89181-79-3 | [Synonyms]
3-Amino-1-methylpyrazole-4-carboxamide
3-amino-1-methyl-1H-Pyrazole-4-carboxamide
1H-Pyrazole-4-carboxamide, 3-amino-1-methyl-
1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI)
3-Amino-1-methyl-1H-pyrazole-4-carboxylic acid amide | [Molecular Formula]
C5H8N4O | [MDL Number]
MFCD08128459 | [MOL File]
89181-79-3.mol | [Molecular Weight]
140.14 |
| Hazard Information | Back Directory | [Synthesis]
GENERAL PROCEDURE: 1-methyl-3-amino-4-cyanopyrazole (0.03 mol) was dissolved in 7 mL of concentrated hydrochloric acid at 0°C and stirred at room temperature for 5 hours. After completion of the reaction, the mixture was poured into ice water and neutralized with 28% ammonia solution to pH 7. The precipitated white precipitate was washed with cold water and dried under vacuum. | [References]
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 5, p. 1751 - 1765
[2] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 784 - 798
[3] Patent: WO2012/30924, 2012, A1. Location in patent: Page/Page column 134 |
|
|