| Identification | Back Directory | [Name]
NSC 698600 | [CAS]
908069-17-0 | [Synonyms]
NSC 698600
Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-5-methyl- | [Molecular Formula]
C14H12N2O2S | [MOL File]
908069-17-0.mol | [Molecular Weight]
272.32 |
| Hazard Information | Back Directory | [Uses]
NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 μM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1]. | [References]
[1] Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89. DOI:10.1016/j.bmc.2011.01.063 |
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