| Identification | Back Directory | [Name]
LHRH, His(5)-Trp(7)-Tyr(8)- | [CAS]
91097-16-4 | [Synonyms]
LHRH, His(5)-Trp(7)-Tyr(8)-
Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidylglycyl-L-tryptophyl-L-tyrosyl-L-prolyl- | [Molecular Formula]
C60H69N17O13 | [MDL Number]
MFCD00167710 | [MOL File]
91097-16-4.mol | [Molecular Weight]
1236.3 |
| Hazard Information | Back Directory | [Uses]
LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken[1][2]. | [in vivo]
LH-RH II (chicken) (10-10-10-8 mg/kg; i.v.; single dose) stimulates increases in the plasma concentrations of luteinizing hormone (LH), which are initiated within 1 min of injection in out-of-lay (OL) and incubating (I) hens but from 5 to 20 min postinjection in laying (L) hens[2].
| [References]
[1] Sharp PJ, et al. Physiological roles of chicken LHRH-I and -II in the control of gonadotrophin release in the domestic chicken. J Endocrinol. 1990 Feb;124(2):291-9. DOI:10.1677/joe.0.1240291
[2] Guémené D, et al. LH responses to chicken luteinizing hormone-releasing hormone I and II in laying, incubating, and out of lay turkey hens. Domest Anim Endocrinol. 1999 Jul;17(1):1-15. DOI:10.1016/s0739-7240(99)00020-x |
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