| Identification | Back Directory | [Name]
DOSPA | [CAS]
913194-16-8 | [Synonyms]
DOSPA HCl salt
N-(2-((S)-2,5-bis(3-aminopropylamino)pentanamido)ethyl)-N,N-dimethyl-2,3-bis((Z)-octadec-9-enyloxy)propan-1-aminium pentahydrochloride
N-(2-((S)-2,5-bis(3-aminopropylamino)pentanamido)ethyl)-N,N-dimethyl-2,3-bis((Z)-octadec-9-enyloxy)propan-1-aminium pentahydrochloride(DOSPA ) | [Molecular Formula]
C54H112Cl2N6O3 | [MOL File]
913194-16-8.mol | [Molecular Weight]
964.43 |
| Hazard Information | Back Directory | [Uses]
DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine. | [References]
[1] Even-Chen S, Barenholz Y. DOTAP cationic liposomes prefer relaxed over supercoiled plasmids.?Biochim Biophys Acta. 2000;1509(1-2):176-188. DOI:10.1016/s0005-2736(00)00292-3 |
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