| Chemical Properties | Back Directory | [Boiling point ]
595.8±50.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
14.54±0.29(Predicted) |
| Hazard Information | Back Directory | [Description]
Karavilagenin D exhibits inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator, and with TPA as a promoter.
Karavilagenin D exhibits inhibition effect against human cancer cell lines. | [Uses]
Karavilagenin D, a cucurbitane-type triterpene isolated from Japanese bitter melon leaves, is a potential tumor-promoting inhibitor[1]. | [References]
[1] Jie Zhang, et al. Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities. Chem Biodivers. 2012 Feb;9(2):428-40. DOI:10.1002/cbdv.201100142 |
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