| Identification | Back Directory | [Name]
JNJ 39220675 | [CAS]
959740-39-7 | [Synonyms]
JNJ 39220675
Methanone, (4-cyclobutylhexahydro-1H-1,4-diazepin-1-yl)[6-(4-fluorophenoxy)-3-pyridinyl]- | [Molecular Formula]
C21H24FN3O2 | [MDL Number]
MFCD30532750 | [MOL File]
959740-39-7.mol | [Molecular Weight]
369.43 |
| Hazard Information | Back Directory | [Uses]
JNJ-39220675 is a selective and brain-penetrating histamine H3 receptor antagonist with activity in regulating alcohol stimulation and reward. JNJ-39220675 is effective in reducing alcohol intake and preference in alcohol-preferring rats. JNJ-39220675 does not affect the ataxic effects of alcohol, the rate of alcohol elimination, or alcohol-induced nucleocapsid dopamine release[1]. | [References]
[1] JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats |
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