1002295-95-5
中文名稱
H-ALA-PRO-GLU-THR-GLU-ARG-ALA-ALA-VAL-ALA-ILE-GLN-ALA-GLN-PHE-ARG-LYS-PHE-GLN-LYS-LYS-LYS-ALA-GLY-SER-NH2
英文名稱
CAMSTATIN
CAS
1002295-95-5
分子式
C122H203N39O34
分子量
2760.16
MOL 文件
1002295-95-5.mol
1002295-95-5 結(jié)構(gòu)式
基本信息
中文別名
H-ALA-PRO-GLU-THR-GLU-ARG-ALA-ALA-VAL-ALA-ILE-GLN-ALA-GLN-PHE-ARG-LYS-PHE-GLN-LYS-LYS-LYS-ALA-GLY-SER-NH2 英文別名
CAMSTATINL-Serinamide, L-alanyl-L-prolyl-L-α-glutamyl-L-threonyl-L-α-glutamyl-L-arginyl-L-alanyl-L-alanyl-L-valyl-L-alanyl-L-isoleucyl-L-glutaminyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-phenylalanyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alanylglycyl-
物理化學性質(zhì)
儲存條件Desiccate at -20°C
形態(tài)粉末
水溶解性Soluble to 1 mg/ml in water
序列Ala-Pro-Glu-Thr-Glu-Arg-Ala-Ala-Val-Ala-Ile-Gln-Ala-Gln-Phe-Arg-Lys-Phe-Gln-Lys-Lys-Lys-Ala-Gly-Ser-NH2
常見問題列表
生物活性
Camstatin 是 PEP-19 智商基序的活性 25-殘基片段，結(jié)合鈣調(diào)蛋白并抑制神經(jīng)元一氧化氮合酶 (NO synthase)。體外研究
Camstatin is a synthetic peptide encompassing the minimal IQ motif of PEP-19 that binds apoCaM and inhibits the activities of the CaM-dependent enzymes neuronal nitric oxide synthase (nNOS) and CaM-kinase II.