1007117-62-5
中文名稱
CMP-NAN SODIUM SALT
英文名稱
CMP-NAN SODIUM SALT
CAS
1007117-62-5
分子式
C20H32N4NaO16P
分子量
638.45
MOL 文件
1007117-62-5.mol
1007117-62-5 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10851(2R,4S,5R,6R)-5-乙酰氨基-2-(((((2R,3S,4R,5R)-5-(4-氨基-2-氧代嘧啶-1(2H)-基)-3,4-二羥基四氫呋喃-2-基)甲氧基)(羥基)磷?；?氧基)-4-羥基-6-((1R,2R)-1,2,3-三羥基丙基)四氫-2H-吡喃-2-羧酸鈉鹽
英文別名
CMP-NAN SODIUM SALTCMP-NANA SODIUM SALT
CMP-SIALIC ACID SODIUM SALT
CYTIDINE 5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID SODIUM SALT
sodium:(2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
物理化學(xué)性質(zhì)
儲存條件−20°C
溶解度PBS (pH 7.2): 10 mg/ml
形態(tài)結(jié)晶固體
顏色White to off-white
生物來源synthetic (organic)
常見問題列表
生物活性
CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) 是 UDP-GlcNAc 2-差向異構(gòu)酶的變構(gòu)抑制劑，UDP-GlcNAc 2-差向異構(gòu)酶可引發(fā)唾液酸合成。CMP-Sialic acid sodium salt 為高爾基唾液酸轉(zhuǎn)移酶提供了底物。體外研究
CMP-Sialic acid (CMP-Neu5Ac), the activated form of Neu5Ac, serves as the common activated sugar donor for all the sialyltransferases to transfer a single sialic acid to an acceptor or a growing oligosaccharide chain. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates.