1015167-40-4
中文名稱
達(dá)比加群?；⒕S葡糖苷酸
英文名稱
Dabigatran Acyl-β-D-Glucuronide
CAS
1015167-40-4
分子式
C31H33N7O9
分子量
647.635
MOL 文件
1015167-40-4.mol
更新日期
2025/10/09 16:48:46
1015167-40-4 結(jié)構(gòu)式
基本信息
中文別名
達(dá)比加群代謝物達(dá)比加群酰基Β維葡糖苷酸
達(dá)比加群?；?D-葡萄糖醛酸
達(dá)比加群?；??-D-葡糖苷酸TFA鹽
達(dá)比加群酯酰基-?-D-葡糖苷酸三氟乙酸鹽
達(dá)比加群?；??-D-葡糖苷酸-D3 TFA鹽
達(dá)比加群?；?-?-D-葡萄糖醛酸 三氟乙酸鹽
達(dá)比加群酰基--?-D-葡萄糖醛酸-D3 三氟乙酸鹽
N-[[2-[[[4-(氨基亞胺甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-2-吡啶基-BETA-丙氨酸 BETA-D-吡喃葡糖酸基酯
英文別名
Dabigatran Acyl GlucuronideDabigatran Acyl-β-D-Glucuronide
Dabigatran Acyl-β-D-Glucuronide
Dabigatran β-Acyl Glucuronide D4
Dabigatran Acyl-Beta-D-Glucuronide
Dabigatran Acyl-?-D-Glucuronide TFA Salt
Dabigatran Acyl-?-D-Glucuronide-D3 TFA Salt
Dabigatran Acyl--D- glucuronide trifluroacetic acid
Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt
Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%)
物理化學(xué)性質(zhì)
熔點>155°C (dec.)
儲存條件Hygroscopic, -20°C Freezer, Under Inert Atmosphere
溶解度可溶于DMSO（微溶）、甲醇（微溶、加熱）、水
形態(tài)固體
顏色灰白色至淺棕色
穩(wěn)定性吸濕性，溶液不穩(wěn)定
應(yīng)用領(lǐng)域
用途1
The major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structur es of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).