1031367-64-2
中文名稱(chēng)
MC70
英文名稱(chēng)
MC70
CAS
1031367-64-2
分子式
C24H25NO3
分子量
375.46
MOL 文件
1031367-64-2.mol
更新日期
2026/03/06 10:49:51
1031367-64-2 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)536.6±50.0 °C(Predicted)
密度1.183±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度可溶于DMSO
酸度系數(shù)(pKa)9.80±0.26(Predicted)
形態(tài)結(jié)晶固體
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
MC-70 is a potent P-gp inhibitor (EC50 = 0.69 μM). Multidrug resistance (MDR) is the major cause of the failure of cancer therapy since this phenomenon generates cancer cells that are unresponsive to chemotherapeutic agents. P-glycoprotein (P-gp) is a well-known membrane transporter expressed in a number of strategic biological barriers, where it exerts a protective effect of paramount importance.