1042672-97-8
中文名稱
N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
英文名稱
N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
CAS
1042672-97-8
分子式
C20H20N4O3S
分子量
396.46
MOL 文件
1042672-97-8.mol
更新日期
2026/05/25 13:08:19
1042672-97-8 結(jié)構(gòu)式
基本信息
中文別名
IRAK 抑制劑 6化合物IRAK INHIBITOR 6
N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
英文別名
CS-647CS-2482
IRAK inhibitor 6
N-[2-methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-
N-(2-Methoxy-4-Morpholinophenyl)-2-(pyridin-3-yl)thiazole-4-carboxaMide
N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
4-ThiazolecarboxaMide, N-[2-Methoxy-4-(4-Morpholinyl)phenyl]-2-(3-pyridinyl)-
所屬類別
生物化工：激動(dòng)劑抑制劑物理化學(xué)性質(zhì)
密度1.335
儲(chǔ)存條件Sealed in dry,Store in freezer, under -20°C
溶解度insoluble in EtOH; insoluble in H2O; ≥9.9 mg/mL in DMSO
酸度系數(shù)(pKa)10.19±0.70(Predicted)
形態(tài)固體
顏色Light brown to brown
N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-13280 | N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰 IRAK inhibitor 6 | 1042672-97-8 | 5mg | 700元 |
| 2026/06/05 | HY-13280 | N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰 IRAK inhibitor 6 | 1042672-97-8 | 10mM * 1mLin DMSO | 770元 |
| 2026/06/05 | HY-13280 | N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰 IRAK inhibitor 6 | 1042672-97-8 | 10mg | 1123元 |
常見問題列表
生物活性
IRAK inhibitor 6 是一種選擇性的Interleukin-1 receptor-associated kinase 4(IRAK4)抑制劑，IC50為 0.16 μM。靶點(diǎn)
| Target | Value |
|
IRAK4
(Cell-free assay) | 0.16 μM |
體外研究
IRAK inhibitor 6 significantly improves potency against IRAK-4. Potency effects additive, IRAK inhibitor 6 is the most active compound among these compound tested.