105277-43-8
105277-43-8 結(jié)構(gòu)式
基本信息
中文別名
化合物 T28318 英文別名
PD 119819PD119819' PD-119819
7-<3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>-4H-1-benzopyran-4-one dihydrochloride
應(yīng)用領(lǐng)域
用途一
PD 119819 is a heterocyclic piperazine and has been identified as an extremely selective DA autoreceptor agonist in tests that include [3H]haloperidol binding, inhibition of spontaneous locomotor activity, inhibition of brain DA synthesis, inhibition of brain DA neuronal firing, stereotypy assessment, and reversal of 6-hydroxydopamine (6-OHDA) induced akinesia in rats.