1070424-33-7
中文名稱(chēng)
化合物 T26821
英文名稱(chēng)
BIPM
CAS
1070424-33-7
分子式
C23H22N2O3
分子量
374.44
MOL 文件
1070424-33-7.mol
1070424-33-7 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
BIPM novel and potent Rho-associated protein kinase 2 (ROCK2) inhibitor. Exposure of SH-SY5Y cells to BIPM led to significant changes in neurite length, cell migration and actin stress fibers. Further experiments demonstrated that BIPM was able to significantly inhibit phosphorylation of cofilin, a regulatory protein of actin cytoskeleton.