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108929-03-9

中文名稱 化合物 T33450
英文名稱 ML 23
CAS 108929-03-9
分子式 C17H16N4O5
MOL 文件 108929-03-9.mol
108929-03-9 結(jié)構(gòu)式 108929-03-9 結(jié)構(gòu)式

基本信息

中文別名
化合物 T33450
英文別名
ML 23
N-(3,5-Dinitrophenyl)-5-methoxy-1H-indole-3-ethanamine
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2,4-dinitroaniline

應(yīng)用領(lǐng)域

用途一
ML 23 is a melatonin analogue in the treatment and management of Parkinson's disease. ML-23 is a potential clinical candidate for the treatment of PD, and the present study has been undertaken to determine the efficacy of ML-23 in the 1-methyl-4-phenyl, 1,2,3,6 tetrahydropyridine (MPTP) model in the common marmoset. On all parameters, ML-23 produced a significant remission from MPTP-induced Parkinsonism, and this effect did not abate when ML-23 treatment was withdrawn. Conversely, a recurrence of Parkinsonian signs was not observed when ML-23 treatment was withdrawn and substituted with oral vehicle.
"108929-03-9" 相關(guān)產(chǎn)品信息
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