11033-22-0
11033-22-0 結(jié)構(gòu)式
基本信息
中文別名
助間型霉素化合物 T23905
英文別名
NSC 277817coformycin
5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-d-ribofuranosyl-imidazo((
(8R)-3-β-D-Ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
(8R)-3,4,7,8-Tetrahydro-3-β-D-ribofuranosylimidazo[4,5-d][1,3]diazepin-8-ol
(r)-3,4,7,8-tetrahydro-3-beta-d-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-o
Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-β-D-ribofuranosyl-, (8R)-
常見問題列表
生物活性
Coformycin 是一種核苷類抗生素，是腺苷脫氨酶 (adenosine deaminase , ADA) 的抑制劑。Coformycin 具有抗腫瘤和抗菌活性。體內(nèi)研究
Coformycin (0.2 mg/kg, ip daily) inhibits adenosine deaminase activity for various tissues, including brain, heart, kidney, liver, etc.
| Animal Model: | Swiss-Webster mice. |
| Dosage: | 0.2 mg/kg. |
| Administration: | IP daily. |
| Result: | Inhibited adenosine deaminase activity for various tissues. |