110816-78-9
110816-78-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 T15676 英文別名
N 556KY-556
5,5'-[[2-(Lysyloxy)propane-1,3-diyl]bisoxy]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl]·2hydrochloride
110816-78-9價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-U00148 | KY-556 | 110816-78-9 | 1 mg | 450元 |
| 2026/06/05 | HY-U00148 | KY-556 | 110816-78-9 | 5 mg | 1120元 |
| 2026/06/05 | HY-U00148 | 110816-78-9 KY-556 | 110816-78-9 | 10 mM * 1 mLin DMSO | 1788元 |
常見(jiàn)問(wèn)題列表
生物活性
KY-556 是一種針對(duì)過(guò)敏性疾病的具有口服活性的色甘酸二鈉 (DSCG) 的前藥。體內(nèi)研究
The oral anti-allergic effect of KY-556 (N-556) is investigated. N-556 (10-100 mg/kg, p.o.) inhibits dose-dependently the 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats, and the duration of action is longer than that of intravenous Disodium cromoglycate (DSCG). N-556 (20 and 100 mg/kg once a day for 20 consecutive days, p.o.) tends to inhibit the histamine release from actively sensitized rat lung fragments. N-556 (100 mg/kg, p.o.) shows the prolongation of survival time in the rat systemic anaphylaxis. N-556 (100 mg/kg, p.o.) significantly inhibits the increased airway resistance in experimental asthma in rats.