115044-69-4
中文名稱
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
英文名稱
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CAS
115044-69-4
分子式
C103H185N31O24S
分子量
2273.83
MOL 文件
115044-69-4.mol
更新日期
2026/05/26 08:24:17
115044-69-4 結(jié)構(gòu)式
基本信息
中文別名
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309),LKKFNARRKLKGAILTTMLA 英文別名
LKKFNARRKLKGAILTTMLACAM KINASE II (290-309)
CALMODULIN BINDING DOMAIN
CALMODULIN DEPENDENT PROTEIN KINASE II
CaM Kinase II (290-309), Calmodulin Antagonist
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CALMODULIN-DEPENDENT PROTEIN KINASE IIFR AGMENT 290
CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CALMODULIN-DEPENDENT PROTEIN KINASE II FRAGMENT 290-309
Calmodulin Binding Domain - CAS 115044-69-4 - Calbiochem
物理化學(xué)性質(zhì)
密度1.37±0.1 g/cm3(Predicted)
儲存條件−20°C
溶解度Soluble in DMSO
形態(tài)白色凍干固體
顏色white
水溶解性water: soluble
序列Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
InChIKeyLRKHMNPQPYICFK-RBGVSSEXSA-N
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 1 mg | 3300元 |
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 5mg | 13000元 |
常見問題列表
生物活性
Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗劑， 抑制抑制Ca2+/鈣調(diào)蛋白依賴性蛋白激酶II的 IC50 值為52 nM。靶點
IC50: 52 nM (calmodulin-dependent protein kinase II)
體外研究
Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC 50 of 52 nM for inhibition of Ca 2+ /calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity.