117041-96-0
117041-96-0 結(jié)構(gòu)式
基本信息
2-甲基檸檬酸三鈉 非對映異構(gòu)體的混合物 (甲基-D3, 98%) 90%+ CP
2-Methylcitric acid trisodium
2-hydroxy-butane-1,2,3-tricarbonoic acid
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS
Trisodium 2-methylcitrate, racemic mixture of diastereomers >=85% (mixture of diastereomers, NMR)
物理化學性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/12/22 | HY-113371A | 2-Methylcitric acid trisodium | 117041-96-0 | 1 mg | 1250元 |
| 2025/12/22 | HY-113371A | TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 2-Methylcitric acid trisodium | 117041-96-0 | 5mg | 3500元 |
| 2025/12/22 | HY-113371A | 2-Methylcitric acid trisodium | 117041-96-0 | 10 mg | 5600元 |
常見問題列表
|
Human Endogenous Metabolite
|
2-Methylcitric acid trisodium impairs glutamate metabolism and induces permeability transition in brain mitochondria.
2-Methylcitric acid trisodium inhibits glutamate dehydrogenase (GDH) activity at concentrations as low as 0.5 mM.
2-Methylcitric acid trisodium (1 mM, 3 mM; 150 seconds) provokes a significant decrease in mitochondrial membrane potential and induced swelling in Ca
2+
-loaded mitochondria supported by different substrates.
2-Methylcitric acid trisodium behaves as a potent inhibitor of glutamate oxidation by inhibiting glutamate dehydrogenase activity and as a permeability transition inducer, disturbing mitochondrial energy homeostasis.
2-Methylcitric acid trisodium does not significantly impair mitochondrial glutamate transport.
2-Methylcitric acid trisodium does not significantly impair glutamate mitochondrial transport in liver mitochondria.