1191450-19-7
中文名稱
BURIXAFOR HYDROBROMIDE
英文名稱
Forodesine
CAS
1191450-19-7
分子式
C27H52BrN8O3P
分子量
647.64
MOL 文件
1191450-19-7.mol
1191450-19-7 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10635 英文別名
Burixafor HBrTG-0054 hydrobromide
Burixafor hydrobromide (TG-0054 hydrobromide)
Burixafor hydrobromide (Synonyms: TG-0054 hydrobromide)
應(yīng)用領(lǐng)域
用途一
Burixafor, also known as TG-0054, is an orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. Burixafor binds to the chemokine receptor CXCR4, thereby preventing the binding of stromal derived factor-1 (SDF-1 or CXCL12) to the CXCR4 receptor and subsequent receptor activation; this may the mobilization of hematopoietic stem and progenitor cells from the bone marrow into blood. Note: Elemental analysis showed it was a salt with 3 HBr and 3 water.常見(jiàn)問(wèn)題列表
概述
Burixafor hydrobromide (TG-0054 hydrobromide) 是具有口服活性的、有效的 CXC 族趨化因子受體 4 (CXCR4) 的拮抗劑，是一種具有潛在研究脈絡(luò)膜新生血管的抗血管生成劑。Burixafor hydrobromide (TG-0054 hydrobromide) 能夠在豬心肌梗死模型中，動(dòng)員間充質(zhì)干細(xì)胞，減輕炎癥反應(yīng)，維持心臟的收縮功能。BURIXAFOR HYDROBROMIDE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-19867A | BURIXAFOR HYDROBROMIDE Burixafor hydrobromide | 1191450-19-7 | 5 mg | 1000元 |
| 2026/06/05 | HY-19867A | BURIXAFOR HYDROBROMIDE Burixafor hydrobromide | 1191450-19-7 | 10 mg | 1500元 |
| 2026/06/05 | HY-19867A | BURIXAFOR HYDROBROMIDE Burixafor hydrobromide | 1191450-19-7 | 10 mM * 1 mL in Water | 1692元 |