119290-87-8
中文名稱
1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,7S,8aS,10aS)-
英文名稱
1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,7S,8aS,10aS)-
CAS
119290-87-8
分子式
C20H30O2
分子量
302.45
MOL 文件
119290-87-8.mol
119290-87-8 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26545 英文別名
NP1302NP 1302: NP-1302
1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,7S,8aS,10aS)-
應(yīng)用領(lǐng)域
用途一
Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum. It has been reported to have anti-inflammatory activities. Acanthoic acid downregulates LPS-induced TNF-α, IL-6 and IL-1β production in BALF, attenuates lung histopathologic changes, and inhibits inflammatory cytokines by stopping TNF-α, IL-6 and IL-1β production and NF-κB activation in LPS-stimulated alveolar macrophages.