1215458-51-7
1215458-51-7 結(jié)構(gòu)式
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-B1106A | 四羥基苯醌水合物 Tetrahydroxyquinone monohydrate | 1215458-51-7 | 100mg | 300元 |
| 2026/06/05 | HY-B1106A | 四羥基苯醌水合物 Tetrahydroxyquinone monohydrate | 1215458-51-7 | 10mM * 1mLin DMSO | 330元 |
常見問題列表
Tetrahydroxyquinone (100-500 μM; 24 hours; HL60 cells) treatment shows cytotoxic for HL60 leukaemia cells by total protein content (IC
50
of 20 μM), phosphatase activity (IC
50
of 40 μM), or by MTT assay (IC
50
of 45 μM). Tetrahydroxyquinone is an efficient inducer of ROS production in HL60 leukaemia cells.
Tetrahydroxyquinone efficiently activates caspase 3 in concentration in excess of 25 μM, stimulates DNA fragmentation at the same concentration and provoke phosphatidylserine exposure.
Tetrahydroxyquinone induces the release of cytochrome c from the mitochondria at concentration as low as 25 μM. Tetrahydroxyquinone treatment also causes increase of phosphorylation of Ser473 in protein kinase B (the Bad kinase for Ser112).