1233082-79-5
中文名稱(chēng)
CS-2123
英文名稱(chēng)
AMpkinone
CAS
1233082-79-5
分子式
C31H23NO6
分子量
505.52
MOL 文件
1233082-79-5.mol
更新日期
2024/11/15 18:20:31
1233082-79-5 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10312 英文別名
CS-2123AMpkinone
[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione, 2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-
物理化學(xué)性質(zhì)
沸點(diǎn)732.7±70.0 °C(Predicted)
密度1.353±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度≤2mg/ml in DMSO;10mg/ml in dimethyl formamide
酸度系數(shù)(pKa)9.01±0.40(Predicted)
形態(tài)結(jié)晶固體
顏色Light yellow to yellow
InChIKeyBRRCHDIWBKOMEC-UHFFFAOYSA-N
SMILESOC1=C(OC)C=CC2=C1OC(C)(C)C3=C2C=CC4=C3C(N(C5=CC=C(C(C6=CC=CC=C6)=O)C=C5)C4=O)=O
CS-2123價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-12831 | CS-2123 Ampkinone | 1233082-79-5 | 2mg | 2560元 |
| 2026/06/05 | HY-12831 | CS-2123 Ampkinone | 1233082-79-5 | 10mM * 1mLin DMSO | 7674元 |
| 2025/12/22 | HY-12831 | CS-2123 Ampkinone | 1233082-79-5 | 5mg | 1600元 |
常見(jiàn)問(wèn)題列表
生物活性
Ampkinone 是一種間接的 AMP 激活蛋白激酶 (AMPK) 激活劑。靶點(diǎn)
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AMPK
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體外研究
Ampkinone stimulates the phosphorylation of AMPK via the indirect activation of AMPK in various cell lines. Ampkinone-mediated activation of AMPK requires the activity of LKB1 and results in increased glucose uptake inmuscle cells.
體內(nèi)研究
Ampkinone-treated DIO mice significantly reduce total body weight and overall fat mass. Histological examination and measurement of lipid parameters show that Ampkinone effectively improves metabolic abnormalities in the DIO mice model.