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124447-81-0

中文名稱 124447-81-0
英文名稱 Amylin (mouse, rat)
CAS 124447-81-0
分子式 C167H272N52O53S2
分子量 3920.39
MOL 文件 124447-81-0.mol
更新日期 2026/07/10 13:20:55
124447-81-0 結(jié)構(gòu)式 124447-81-0 結(jié)構(gòu)式

基本信息

中文別名
RAT AMYLIN
英文別名
Ratamylin
Amylin (mouse, rat)
IAPP (Mouse, rat), Islet aMyloid polypeptide (Mouse, rat)
AMylin (Mouse, rat) IAPP (Mouse, rat), Islet aMyloid polypeptide (Mouse, rat)
H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
Amylin (mouse, rat) trifluoroacetate salt H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 trifluoroacetate salt (Disulfide bond)

物理化學性質(zhì)

形態(tài)Solid
顏色White to off-white
序列Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7)
124447-81-0價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2026/06/05HY-P1464124447-81-0
Amylin, amide, rat
124447-81-0500 μg1600元
2026/06/05HY-P1464124447-81-0
Amylin, amide, rat
124447-81-01 mg2600元

常見問題列表

生物活性
Amylin, amide, rat 是一種有效的高親和力的胰淀素受體 AMY1 和 AMY3 的配體。
靶點

Amylin receptor AMY1 and AMY3

體外研究

Amylin is an important, but poorly understood, 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. Amylin is a member of the calcitonin (CT) family of peptides, which includes CT itself, the CGRPs comprising two variants (αCGRP and βCGRP), adrenomedullin (AM) and AM2 (intermedin). Amylin is a centrally acting, neuroendocrine hormone synthesized with insulin in the beta cells of pancreatic islets. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the counter-regulatory hormone glucagon and inducing meal-ending satiety. Amylin functions as a glucoregulatory and satiety-inducing hormone, which is protective against postprandial spikes in blood glucose and overeating.

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