1264754-13-3
中文名稱
1264754-13-3
英文名稱
E3 ligase Ligand 5
CAS
1264754-13-3
分子式
C19H11F3N2O4S
分子量
420.36
MOL 文件
1264754-13-3.mol
更新日期
2026/06/01 11:31:41
1264754-13-3 結(jié)構(gòu)式
基本信息
中文別名
化合物PROTAC ERRΑ LIGAND 1 英文別名
E3 ligase Ligand 5PROTAC ERRα ligand 1
PROTAC ERRα ligand 1
4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]-3-(trifluoromethyl)benzonitrile
物理化學(xué)性質(zhì)
密度1.53±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)7.31±0.20(Predicted)
形態(tài)Solid
顏色Light yellow to green yellow
應(yīng)用領(lǐng)域
用途一
E3L-4133, also known as E3 ligase Ligand 5, is an E3 ligase Ligand that can be used in PROTAC (proteolysis targeting chimera) technology to engage an E3 ubiquitin ligase. PROTAC is a two-headed molecule capable of removing specific unwanted proteins.