1270138-41-4
中文名稱
NSI-189磷酸鹽
英文名稱
NSI-189 Phosphate
CAS
1270138-41-4
分子式
C22H33N4O5P
分子量
464.495
MOL 文件
1270138-41-4.mol
更新日期
2024/12/23 09:09:17
1270138-41-4 結(jié)構(gòu)式
基本信息
中文別名
NSI-189 磷酸NSI-189磷酸鹽
英文別名
NSI-189 H3PO4NSI-189 phosphate
phosphoric acid/NSI-189 phosphate
(4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone,phosphoric acid
所屬類別
有機原料：羧酸類化合物及衍生物物理化學(xué)性質(zhì)
形態(tài)Solid
顏色White to off-white
InChIKeyLWHMGALTTIYPJU-UHFFFAOYSA-N
SMILESP(O)(O)(O)=O.C(N1CCN(CC2=CC=CC=C2)CC1)(C1=CC=CN=C1NCCC(C)C)=O
應(yīng)用領(lǐng)域
用途一
NSI-189 is a novel oral drug which was developed by Neuralstem for the treatment of cognitive disorders. Now the drug is being tested in phase II of clinical trials in patients suffering from major depressive disorder. The mechanism of NSI-189 action is explained by its ability to stimulate the generation of new neurons in the hippocampus, however the exact target molecule is still unknown.