130743-07-6
130743-07-6 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
密度1.45±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: soluble; DMSO: soluble; Ethanol: slightly soluble; Methanol: slightly soluble
酸度系數(shù)(pKa)6.91±0.40(Predicted)
形態(tài)黃色粉末
常見問(wèn)題列表
生物活性
Quinaldopeptin 是可從 Streptoverticillium album 中分離得到的喹諾霉素抗生素，對(duì)革蘭氏陽(yáng)性菌和厭氧菌具有高活性，對(duì)B16 黑色素瘤細(xì)胞具有明顯毒性。體外研究
Quinaldopeptin is quite active against B16-F10 cells with IC 50 values approximately 3-fold superior to that of chromomycin A 3 .
體內(nèi)研究
Quinaldopeptin shows slight prolongation of life-span in P388-bearing mice at 0.03~0.01 mg/kg, but the antitumor activities is quite limited.