1308256-94-1

中文名稱 (ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-聯(lián)苯]-4-丙酸

英文名稱 LHW090-A7

CAS 1308256-94-1

分子式 C20H22ClNO4

分子量 375.85

MOL 文件 1308256-94-1.mol

更新日期 2026/07/27 12:22:47

1308256-94-1 結(jié)構(gòu)式

基本信息物理化學(xué)性質(zhì) 應(yīng)用領(lǐng)域圖譜信息 (ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-聯(lián)苯]-4-丙酸價(jià)格(試劑級)

基本信息

中文別名

(ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-聯(lián)苯]-4-丙酸

英文別名

CS-2208
EOS-61103
LHW090-A7
(αS)-3'-Chloro-α-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino][1,1'-biphenyl]-4-propanoic acid
(S)-3-(3'-Chloro-[1,1'-biphenyl]-4-yl)-2-(((S)-1-ethoxy-1-oxopropan-2-yl)amino)propanoic acid
[1,1'-Biphenyl]-4-propanoic acid, 3'-chloro-α-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino]-, (αS)-
Sodium (2S)-3-(3'-chloro-[1,1'-biphenyl]-4-yl)-2-{[(2S)-1-ethoxy-1-oxopropan-2-yl]amino}propanoate
(alphaS)-3'-Chloro-alpha-[[(1S)-2-ethoxy-1-methyl-2-oxoethyl]amino][1,1'-biphenyl]-4-propanoic acid

所屬類別

生物化工：激動(dòng)劑抑制劑

物理化學(xué)性質(zhì)

溶解度DMSO: 5 mg/ml
Ethanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml

InChIInChI=1/C20H22ClNO4/c1-3-26-20(25)13(2)22-18(19(23)24)11-14-7-9-15(10-8-14)16-5-4-6-17(21)12-16/h4-10,12-13,18,22H,3,11H2,1-2H3,(H,23,24)/t13-,18-/s3

InChIKeyPWYAUIUPDMSWJH-CODVNQPLNA-N

SMILESC(O)(=O)[C@@H](N[C@@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC(Cl)=C2)C=C1 |&1:3,5,r|

應(yīng)用領(lǐng)域

用途一

LHW090-A7 is a compound developed as an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins. Inhibitors of NEP have been shown to increase plasma levels of endogenous atrial natriuretic peptides and, as such, are expected to induce natriuretic and diuretic effects.

圖譜信息

(ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-聯(lián)苯]-4-丙酸(1308256-94-1)核磁圖(¹HNMR)

(ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-聯(lián)苯]-4-丙酸價(jià)格(試劑級)