1337482-15-1
中文名稱
索氟布韋雜質
英文名稱
Sofosbuvir IMpurity C
CAS
1337482-15-1
分子式
C22H29FN3O9P
分子量
529.45
MOL 文件
1337482-15-1.mol
更新日期
2025/11/03 09:40:11
1337482-15-1 結構式
基本信息
中文別名
索氟布韋雜質索非布韋雜質G
索菲布韋雜質G
索福斯布韋雜質C
索磷布韋雜質20
索氟布韋雜質15
索非布韋雜質08
索伐布韋位置異構雜質
索非布韋雜質Y008005-G
英文別名
Ofosbuvi rimpuritySofosbuvir impurity G
sofosbuvir impurity Y008005-G
Sofosbuvir IMpurity C 1337482-15-1
Sofosbuvir 5'-Desphosphate 3’-O-[(S)-Phosphate]
L-Alanine, N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl]-, 1-methylethyl ester
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosph
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alanite
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
所屬類別
分析化學：藥典標準品和雜質標準品物理化學性質
密度1.41±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度soluble in No data available
酸度系數(pKa)9.39±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
概述
索氟布韋雜質 是 Sofosbuvir 的非對映異構體，是 Sofosbuvir 的雜質。Sofosbuvir (PSI-7977) 是 HCV RNA復制的抑制劑，表現出有效的抗丙型肝炎病毒活性。