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1354567-82-0

中文名稱 5MG
英文名稱 Zotiraciclib diHCl (TG-02, SB-1317)
CAS 1354567-82-0
分子式 C23H25ClN4O
分子量 408.93
MOL 文件 1354567-82-0.mol
1354567-82-0 結(jié)構(gòu)式 1354567-82-0 結(jié)構(gòu)式

基本信息

中文別名
化合物 ZOTIRACICLIB HCL
英文別名
Zotiraciclib diHCl (TG-02, SB-1317)

應(yīng)用領(lǐng)域

用途一
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
"1354567-82-0" 相關(guān)產(chǎn)品信息
1204918-72-8 937270-47-8
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