13571-44-3
中文名稱
化合物VPC-70063
英文名稱
Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-
CAS
13571-44-3
分子式
C16H12F6N2S
分子量
378.34
MOL 文件
13571-44-3.mol
13571-44-3 結(jié)構(gòu)式
基本信息
中文別名
化合物VPC-70063化合物VPC-70063,10 MM DMSO 溶液
英文別名
VPC-70063Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-
物理化學(xué)性質(zhì)
熔點(diǎn)151-153 °C
沸點(diǎn)361.7±52.0 °C(Predicted)
密度1.417±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)11.80±0.70(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
VPC-70063 is a Myc-Max inhibitor. VPC-70067 is a close analog of the previously identified Myc inhibitor 10058-F4. VPC-70063, of a chemically different scaffold, was the best performer in a panel of in vitro assays, and the forerunner for future hit-to-lead optimization efforts.