137004-80-9
中文名稱
137004-80-9
英文名稱
Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-
CAS
137004-80-9
分子式
C25H35NO6S
分子量
477.613
MOL 文件
137004-80-9.mol
137004-80-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 T12404 英文別名
CCK-A receptor inhibitor 1Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-
物理化學(xué)性質(zhì)
沸點(diǎn)705.1±60.0 °C(Predicted)
密度1.187±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)4.47±0.10(Predicted)
常見問題列表
生物活性
CCK-A receptor inhibitor 1 是一種縮膽囊素 A (cholecystokinin A, CCK-A) 受體抑制劑，IC50 為 340 nM。靶點(diǎn)
IC50: 340 nM (CCK-A receptor)
體外研究
CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains.