137361-05-8
中文名稱
N-OMEGA-PROPYL-L-ARGININE
英文名稱
N-OMEGA-PROPYL-L-ARGININE
CAS
137361-05-8
分子式
C9H20N4O2
MDL 編號(hào)
MFCD01320455
分子量
216.28
MOL 文件
137361-05-8.mol
137361-05-8 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
熔點(diǎn)198-200?C
沸點(diǎn)366.5±52.0 °C(Predicted)
密度1.24±0.1 g/cm3(Predicted)
儲(chǔ)存條件Desiccate at RT
溶解度可溶于氯仿（少許）、甲醇（少許）
酸度系數(shù)(pKa)2.50±0.24(Predicted)
形態(tài)白色至類白色固體
顏色白色
穩(wěn)定性非常吸濕
CAS 數(shù)據(jù)庫137361-05-8(CAS DataBase Reference)
N-OMEGA-PROPYL-L-ARGININE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-102062 | Nω-Propyl-L-arginine | 137361-05-8 | 5 mg | 940元 |
| 2026/06/05 | HY-102062 | N-OMEGA-PROPYL-L-ARGININE Nω-Propyl-L-arginine | 137361-05-8 | 10 mM * 1 mL in Water | 1034元 |
| 2026/06/05 | HY-102062 | Nω-Propyl-L-arginine | 137361-05-8 | 10 mg | 1500元 |
常見問題列表
生物活性
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) 是一種高效、競(jìng)爭(zhēng)性、高選擇性的神經(jīng)型一氧化氮合酶 (nNOS) 抑制劑，Ki為 57 nM。Nω-Propyl-L-arginine 對(duì) nNOS 的選擇性是內(nèi)皮型一氧化氮合酶 (eNOS) 的 149 倍。體內(nèi)研究
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity.
| Animal Model: | Male NMRI mice (30-40 g) (phencyclidine-induced stimulation) |
| Dosage: | 20 mg/kg |
| Administration: | I.p. |
| Result: | Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |