138559-60-1
中文名稱
AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2
CAS
138559-60-1
分子式
C45H66N18O7S
分子量
1003.19
MOL 文件
138559-60-1.mol
138559-60-1 結(jié)構(gòu)式
AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-125567 | AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2 Antileukinate | 138559-60-1 | 500 μg | 2527元 |
常見問題列表
生物活性
Antileukinate 是一種六肽，是有效的 CXC 趨化因子受體 (CXCR) 抑制劑。Antileukinate 能抑制中性粒細(xì)胞趨化和活化。Antileukinate 可用于急性炎癥和損傷的研究。體外研究
Antileukinate inhibits the binding of human eotaxin to human eosinophils with an IC
50
of 8.2 μM.
Antileukinate (10-100 μM; 2 hours) significantly suppresses eosinophil chemotaxis to human eotaxin.
體內(nèi)研究
Antileukinate (52.63 mg/kg; s.c.) protectes mice against acute pancreatitis and associated lung injury.
Antileukinate (5mg/kg; s.c.) inhibits the interaction between murine eotaxin and murine eosinophil.
| Animal Model: | Swiss mice (20-25g) |
| Dosage: | 52.63 mg/kg |
| Administration: | Subcutaneous injection |
| Result: | Reduced pancreatic edema induced by Caerulein (50 μg/kg). |