139220-18-1
英文名稱
4,12-Dioxa-20-thia-21-azabicyclo[16.2.1]heneicosa-1(21),6,8,18-tetraene-5,13-dione,15-aMino-3-[(1E,3E,5E)-7-(diMethylaMino)-2,5-diMethyl-1,3,5-heptatrien-1-yl]-9,11,17-triMethyl-,(3S,6Z,8E,11S,15R,17S)-
CAS
139220-18-1
分子式
C31H45N3O4S
分子量
555.772
MOL 文件
139220-18-1.mol
139220-18-1 結(jié)構(gòu)式
基本信息
英文別名
(-)-pateamine4,12-Dioxa-20-thia-21-azabicyclo[16.2.1]heneicosa-1(21),6,8,18-tetraene-5,13-dione,15-aMino-3-[(1E,3E,5E)-7-(diMethylaMino)-2,5-diMethyl-1,3,5-heptatrien-1-yl]-9,11,17-triMethyl-,(3S,6Z,8E,11S,15R,17S)-
應(yīng)用領(lǐng)域
用途一
Pateamine A is a marine macrolide that is isolated from the sponge Mycale hentscheli and exhibits anticancer and antiviral properties. It has a role as a marine metabolite, an antiviral agent, an antineoplastic agent, and a eukaryotic initiation factor 4F inhibitor. It is a macrolide, a member of 1,3-thiazoles, a tertiary amino compound, a primary amino compound, and an olefinic compound. Pateamine A an inhibitor of eukaryotic translation.