139601-96-0
中文名稱
enopeptin A
英文名稱
enopeptin A
CAS
139601-96-0
分子式
C47H57N7O11
分子量
896.005
MOL 文件
139601-96-0.mol
139601-96-0 結(jié)構(gòu)式
基本信息
中文別名
依諾肽 英文別名
enopeptin AODKIYTBYJKALOK-BKZRIAMSSA-N
N-[[(2E,4E,6E,8E,10E)-12-(2-Hydroxy-5-oxo-1-cyclopentenylamino)-1,12-dioxo-2,4,6,8,10-dodecapentenyl]-L-Phe-]cyclo[L-Ser*-L-Pro-N-methyl-L-Ala-L-Ala-4β-methyl-L-Pro-]
應用領(lǐng)域
用途一
Enopeptin A is an unusual depsipeptide featuring a pentaenone side chain, reported as an antiviral by researchers at RIKEN in 1991. Enopeptin A has potent antibacterial activity against Gram positive and Gram negative bacteria, including MRSA. Enopeptin A is the most non-polar of the acyldepsipeptide (ADEP) antibiotics which include the recently rediscovered compounds, A54556 A and B, that act by activating and disregulating Clp-family proteins.