139726-35-5
139726-35-5 結(jié)構(gòu)式
基本信息
遠(yuǎn)志蔗糖酯A
細(xì)葉遠(yuǎn)志甙 A
細(xì)葉遠(yuǎn)志苷 A
細(xì)葉遠(yuǎn)志苷A對照品
細(xì)葉遠(yuǎn)志苷A標(biāo)準(zhǔn)品
細(xì)葉遠(yuǎn)志苷A(遠(yuǎn)志糖苷A)
α-D-Glucopyranoside, 3-O-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-β-D-fructofuranosyl, 6-(4-hydroxybenzoate)
(E)-(3,4,5-trihydroxy-6-((4-hydroxy-3-((3-(4-hydroxy-3,5-dimethoxyphenyl)acryloyl)oxy)-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl 4-hydroxybenzoate
物理化學(xué)性質(zhì)
常見問題列表
近年來，遠(yuǎn)志科中此類化學(xué)成分的研究越來越多，其腦保護(hù)作用和抗老化作用越來越受到重視。我們的研究表明西伯利亞遠(yuǎn)志糖A1(sibiricoseA1，1)，西伯利亞遠(yuǎn)志糖A5(sibiricoseA5，2)對谷氨酸造成的PC12細(xì)胞損傷均有一定的保護(hù)作用在藥理學(xué)抑郁模型有顯著的抗抑郁活性。細(xì)葉遠(yuǎn)志苷A是遠(yuǎn)志中的活性提取物，對其的研究也越來越多。
細(xì)葉遠(yuǎn)志苷A是遠(yuǎn)志中的活性提取物，近年來，遠(yuǎn)志科中此類化學(xué)成分的研究越來越多，其腦保護(hù)作用和抗老化作用越來越受到重視。
Tenuifoliside A (6-30 μM; 24 hours) increases the C6 cells viability significantly by concentration dependent manner. But the viability of the 60 μM treatment group is suppressed. Only 60 μM TFSA induced the release of LDH, shows a toxic effect. Tenuifoliside A (10 μM; 2, 5, 7, 10, 15, 30, 45 and 60 mins) elicits a rapid (starting at 2 min) and marked induction of ERK1/2 phosphorylation peaking at 5 min. And,the enhanced levels of phospho-ERK induced by TFSA are partially blocked by ERK inhibitor U0126.