1404-64-4
1404-64-4 結(jié)構(gòu)式
基本信息
中文別名
稀疏霉素司帕霉素
司帕索霉素
(+)-司帕索霉素
化合物 T24819
U 19183|||B 120121L19|||B120121L19|||U-19183|||U19183
英文別名
U-19183nsc59729
Aids012106
B 120121L19
Aids-012106
sparsomycin
Sparsomycin from Streptomyces sparsogenes
(E)-N-[(S)-1-(Hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxopyrimidine-5-yl)propenamide
2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[(R)-[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-
物理化學(xué)性質(zhì)
熔點(diǎn)208-209° (dec)
比旋光度D25 +69° (c = 0.5 in water)
密度1.3893 (rough estimate)
折射率1.6390 (estimate)
儲(chǔ)存條件2-8°C
溶解度DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
酸度系數(shù)(pKa)8.67 in water, 9.05 in 40% ethanol
形態(tài)A solid
顏色White to off-white
安全數(shù)據(jù)
危險(xiǎn)品標(biāo)志T+
危險(xiǎn)類別碼28
安全說明28-36/37-45
危險(xiǎn)品運(yùn)輸編號UN 2811 6.1/PG 2
RTECS號WG5850000
毒性LD50 in dogs, rats, mice (mg/kg): 0.5-1.0, 2.25, 4.32 i.v. (Ottenheijm, 1986); LD50 i.p. in mice: 2.4 mg/kg (Owen)