1422423-23-1
1422423-23-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T27258 英文別名
EMICORONPyreno[2,1,10-def:7,8,9-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone, 13-(1-pieridinyl)-2,5,9-tris[2-(1-pieridinyl)ethyl]-
應(yīng)用領(lǐng)域
用途一
Emicoron is a multi-targeting G4 ligand. Emicoron showed Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer. EMICORON showed a marked therapeutic efficacy, as it inhibited the growth of patient-derived xenografts (PDX) and orthotopic colon cancer and strongly reduced the dissemination of tumor cells to lymph nodes, intestine, stomach, and liver. EMICORON had an unprecedented antitumor activity warranting further studies of EMICORON-based combination treatments.