1445790-55-5
中文名稱
4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide
英文名稱
4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide
CAS
1445790-55-5
分子式
C18H16F4N2O4S
分子量
432.39
MOL 文件
1445790-55-5.mol
更新日期
2024/11/01 22:00:08
1445790-55-5 結(jié)構(gòu)式
基本信息
中文別名
化合物NVR 3-7784-氟-3-[(4-羥基-1-哌啶基)磺酰基]-N-(3,4,5-三氟苯基)苯甲酰胺
英文別名
4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamideBenzamide, 4-fluoro-3-[(4-hydroxy-1-piperidinyl)sulfonyl]-N-(3,4,5-trifluorophenyl)-
物理化學(xué)性質(zhì)
溶解度DMSO: Soluble: =10 mg/mL
Ethanol: Soluble: =10 mg/mL
Ethanol: Soluble: =10 mg/mL
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40?μM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos(t)ide inhibitors of HBV replication.4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-124600R | 4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide NVR 3-778 (Standard) | 1445790-55-5 | 1 mg | 1500元 |
| 2026/06/05 | HY-124600R | 4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide NVR 3-778 (Standard) | 1445790-55-5 | 5 mg | 3000元 |
| 2026/06/05 | HY-124600R | 4-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide NVR 3-778 (Standard) | 1445790-55-5 | 10 mg | 4600元 |