146064-00-8
中文名稱
化合物 T23958
英文名稱
dactylocycline D
CAS
146064-00-8
分子式
C33H42ClN3O14
分子量
740.16
MOL 文件
146064-00-8.mol
146064-00-8 結(jié)構(gòu)式
基本信息
中文別名
指孢環(huán)素 D化合物 T23958
英文別名
dactylocycline D2-Naphthacenecarboxamide, 6-[[3-[(acetyloxy)amino]-2,3,6-trideoxy-3-C-methyl-4-O-methyl-α-L-arabino-hexopyranosyl]oxy]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-, [4R-(4α,4aα,5aα,6α,12aα)]- (9CI)
應(yīng)用領(lǐng)域
用途一
Dactylocyclines is novel tetracycline derivatives produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp. (ATCC 53693), a producer of several novel tetracycline derivatives. The major fermentation products, dactylocyclines A and B, were purified and MIC values determined against tetracycline-resistant and tetracycline-sensitive Gram-positive bacteria. The dactylocyclines represent the first naturally occurring tetracycline C2 amides which lack cross resistance with tetracycline.