146554-87-2
中文名稱(chēng)
化合物 T27912
英文名稱(chēng)
LY 290324
CAS
146554-87-2
分子式
C29H24Cl2N6
分子量
527.45
MOL 文件
146554-87-2.mol
146554-87-2 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
LY 290324 is an orally active, potent and selective cysteinyl leukotriene ((LTD4) receptor antagonist. In vitro, LY290324 was a potent and persistent antagonist of the contractile responses to LTD4 and LTE4 with pA2 values of 9.1 +/- 0.2 and 8.9 +/- 0.17 respectively. It is also effective in reducing antigen-induced bronchospasm in immunologically sensitised animals.