148849-68-7
中文名稱
伊伐布雷定雜質(zhì)1
英文名稱
ent-Ivabradine Hydrochloride
CAS
148849-68-7
分子式
C27H37ClN2O5
分子量
505.05
MOL 文件
148849-68-7.mol
148849-68-7 結(jié)構(gòu)式
基本信息
中文別名
伊伐布雷定雜質(zhì)1伊伐布雷定 R異構(gòu)體
伊伐布雷定R-異構(gòu)體HCL
鹽酸伊伐布雷定雜質(zhì)R-異構(gòu)體
伊伐布雷定R異構(gòu)體雜質(zhì)鹽酸鹽
伊伐布雷定R-異構(gòu)體 鹽酸鹽
3-[3-[[(7R)-3,4-二甲氧基-8-雙環(huán)[4.2.0]辛-1,3,5-三烯]甲基-甲氨基]丙基]-7,8-二甲氧基-2,5-二氫-1H-3-苯并氮雜卓-4-酮鹽酸鹽
英文別名
I-3015Ivabradine R-Isomer HCl
Ivabradine HCl R-Isomer
IIvabradine R-Isomer HCl
ent-Ivabradine Hydrochloride
Ivabradine R-Isomer hydrochloride
3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one)
3-[3-[[[(7R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
(R)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
儲(chǔ)存條件-10 to -25°C
溶解度DMSO (Slightly), Methanol (Slightly)
形態(tài)Solid
顏色White to Light Beige
穩(wěn)定性Hygroscopic
主要應(yīng)用pharmaceutical small molecule
應(yīng)用領(lǐng)域
用途一
3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one) is an impurity of 3,3''-(Propane-1,3-diyl)bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) (P760340); an impurity in the synthesis of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also antianginal.