149400-88-4
中文名稱
SARDOMOZIDE
英文名稱
4-amidinoindan-1-one 2'-amidinohydrazone
CAS
149400-88-4
分子式
C11H14N6
分子量
230.274
MOL 文件
149400-88-4.mol
149400-88-4 結(jié)構(gòu)式
基本信息
中文別名
化合物 T128332-(4-甲脒基-2,3-二氫-1H-茚-1-亞基)肼甲脒
英文別名
SAM 486ACGP 48664
SardoMozide
4-amidinoindan-1-one 2'-amidinohydrazone
(E)-2-(4-carbaMiMidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinec
2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide
(E)-2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide
Hydrazinecarboximidamide, 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]-
物理化學(xué)性質(zhì)
沸點(diǎn)438.8±55.0 °C(Predicted)
密度1.54±0.1 g/cm3(Predicted)
儲(chǔ)存條件Keep in dark place,Sealed in dry,2-8°C
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)11.54±0.20(Predicted)
SARDOMOZIDE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-13746 | SARDOMOZIDE Sardomozide | 149400-88-4 | 5 mg | 1260元 |
| 2026/06/05 | HY-13746 | SARDOMOZIDE Sardomozide | 149400-88-4 | 10 mM * 1 mL in DMSO | 1386元 |
| 2026/06/05 | HY-13746 | SARDOMOZIDE Sardomozide | 149400-88-4 | 10 mg | 2100元 |
常見問(wèn)題列表
生物活性
Sardomozide 是一種 S-腺苷甲硫氨酸脫羧酶 (SAMDC) 抑制劑，其 IC50 值為 5 nM。靶點(diǎn)
IC50: 5 nM (SAMDC)
體外研究
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.