153559-46-7
中文名稱
4-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸
英文名稱
4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic acid
CAS
153559-46-7
分子式
C23H26O3
分子量
350.45
MOL 文件
153559-46-7.mol
更新日期
2024/03/25 23:32:35
153559-46-7 結(jié)構(gòu)式
基本信息
中文別名
蓓薩羅丁 中間體44-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸
英文別名
LG-1000644-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)
4-(3,5,5,8,8-pentaMethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-phthalenyl)carbonyl]benzoic acid
4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic acid
Benzoic acid, 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]-
所屬類別
化學(xué)試劑：多環(huán)化合物物理化學(xué)性質(zhì)
熔點(diǎn)198-199 °C
沸點(diǎn)491.4±45.0 °C(Predicted)
密度1.095
儲(chǔ)存條件Inert atmosphere,Room Temperature
溶解度Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Slightly)
酸度系數(shù)(pKa)3.74±0.10(Predicted)
形態(tài)Solid
顏色White to Off-White
InChIInChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-6-8-16(9-7-15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)
InChIKeyQADGBOQVBUXZKO-UHFFFAOYSA-N
SMILESC(O)(=O)C1=CC=C(C(C2=C(C)C=C3C(=C2)C(C)(C)CCC3(C)C)=O)C=C1
4-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-104070 | 4-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸 LG-100064 | 153559-46-7 | 1 mg | 320元 |
| 2026/06/05 | HY-104070 | 4-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸 LG-100064 | 153559-46-7 | 5mg | 800元 |
| 2026/06/05 | HY-104070 | 4-[(5,6,7,8-四氫-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸 LG-100064 | 153559-46-7 | 10mM * 1mLin DMSO | 880元 |
常見(jiàn)問(wèn)題列表
生物活性
LG-100064 是一種類視黃醇 X 受體 (retinoid-X-receptor (RXR)) 激動(dòng)劑，對(duì) RXRα，RXRβ 和 RXRγ 的 EC50 值分別為 330 nM，200 nM 和 260 nM；LG-100064 可用于癌癥研究。靶點(diǎn)
EC50: 330 nM (RXRα), 200 nM (RXRβ), 260 nM (RXRγ)
體外研究
LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC 50 s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ. LG-100064 shows no effect on RARα/β/γ (EC 50 , >10000 nM).