1562024-11-6
中文名稱
2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27
英文名稱
Hs 27
CAS
1562024-11-6
分子式
C52H60N6O12S
分子量
993.13
MOL 文件
1562024-11-6.mol
更新日期
2026/06/04 14:21:29
1562024-11-6 結(jié)構(gòu)式
基本信息
中文別名
人包皮皮膚成纖維細(xì)胞HS27 人皮膚成纖維細(xì)胞系
HS27細(xì)胞:人皮膚成纖維細(xì)胞系
HS27人皮膚成纖維復(fù)蘇細(xì)胞(附STR鑒定報告)
2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18
英文別名
Hs 27HS27
HS-27
HS 27
2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thio,HS-27
2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27
Benzamide, 2-[[21-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-21-thioxo-4,7,10,13,16-pentaoxa-20-azaheneicos-1-yl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)-
所屬類別
生物：人細(xì)胞系物理化學(xué)性質(zhì)
沸點1095.1±75.0 °C(Predicted)
密度1.39±0.1 g/cm3(Predicted)
儲存條件-196°C
溶解度DMSO: 125 mg/mL (125.86 mM)
酸度系數(shù)(pKa)9.33±0.20(Predicted)
形態(tài)Solid
顏色Yellow to orange
HS-27價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-130851 | HS-27 | 1562024-11-6 | 1 mg | 1150元 |
| 2026/06/05 | HY-130851 | 2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27 HS-27 | 1562024-11-6 | 5mg | 2700元 |
| 2026/06/05 | HY-130851 | 2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27 HS-27 | 1562024-11-6 | 10mg | 4200元 |
常見問題列表
生物活性
HS-27，一種熒光 Hsp90 抑制劑，檢測完整組織標(biāo)本表面 Hsp90 的表達(dá)。HS-27 由 SNX-5422 的核心元素組成，SNX-5422 是一種 Hsp90 抑制劑，通過 PEG 連接物與熒光素衍生物 (異硫氰酸熒光素或 FITC) 連接，后者與外周表達(dá)的 Hsp90 結(jié)合。HS-27 在乳腺癌的觀察與研究中有潛在的應(yīng)用。靶點
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HSP90
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體外研究
HS-27 labels all receptor subtypes of breast cancer, but not normal cells, and specifically binds to Hsp90 expressed on the surface of breast cancer cells before being internalized. HS-27 fluorescence is greater in tumor than non-tumor tissue.