158364-59-1
中文名稱
158364-59-1
英文名稱
Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester
CAS
158364-59-1
分子式
C19H22N4O2
分子量
338.4
MOL 文件
158364-59-1.mol
158364-59-1 結構式
基本信息
中文別名
普馬拉唑化合物 T16682
英文別名
PUMAPRAZOLECarbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester
所屬類別
生物：拮抗劑物理化學性質(zhì)
密度1.21±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)13.67±0.70(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
158364-59-1價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-19223 | 普馬拉唑 Pumaprazole | 158364-59-1 | 5mg | 2500元 |
| 2026/06/05 | HY-19223 | 158364-59-1 Pumaprazole | 158364-59-1 | 10 mM * 1 mLin DMSO | 2750元 |
| 2026/06/05 | HY-19223 | 普馬拉唑 Pumaprazole | 158364-59-1 | 10mg | 4000元 |
常見問題列表
生物活性
Pumaprazole 是一種可逆性質(zhì)子泵拮抗劑。靶點
proton pump
體內(nèi)研究
Pumaprazole is a reversible proton pump antagonist. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compare to ranitidine. Pumaprazole displays identical ID 50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23) and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect.